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566-48-3 Raw Steroid Powders Formestane for Antitumor Anti-estrogenic Agent

Good quality SARMs Steroids for sales
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566-48-3 Raw Steroid Powders Formestane for Antitumor Anti-estrogenic Agent

China 566-48-3 Raw Steroid Powders Formestane for Antitumor Anti-estrogenic Agent supplier

Large Image :  566-48-3 Raw Steroid Powders Formestane for Antitumor Anti-estrogenic Agent

Product Details:

Place of Origin: China
Brand Name: Amandary
Certification: HSE, ISO 9001, USP, BP
Model Number: 566-48-3

Payment & Shipping Terms:

Minimum Order Quantity: Negotiable
Price: Negotiable
Packaging Details: As you require
Delivery Time: 12 hours within your payment is received
Payment Terms: T/T, Western Union, Money Gram, Bitcoin
Supply Ability: 1000kg/month
Detailed Product Description
CAS: 566-48-3 Purity: >99%
Appearance: White Powder Specification: GMP, ISO 9001, USP
Formula: C19h26o3 Payment: T/T, Western Union And Money Gram

566-48-3 Raw Steroid Powders Formestane for Antitumor Anti-estrogenic Agent

 

skype:Amandary
whatsAPP:0086 18108459312
e-Mail:puresteroids@ycphar.com

 

Basic Info


Formestane(Lentaron)
Name:Formestane(Lentaron)
Synonyms:4-hydroxy-androst-4-ene-17-dione;4-hydroxy-delta(sub4)-androstenedione;4-HYDROXYANDROST-4-ENE-3,17-DIONE;4-HYDROXYANDROSTENEDIONE;4-HYDROXY-4-ANDROSTENE-3,17-DIONE;4-ANDROSTEN-4-OL-3,17-DIONE;4-OHA;CGP-32349
MF:C19H26O3
MW:302.41
Usage:An antitumor drug. An aromatase inhibitor
Dosage: 250mg, 1 time every two weeks, as the arm deep intramuscular injection.


Product Description


Formestane was the first selective, type I, steroidal aromatase inhibitor used in the treatment of estrogen-receptor positive breast cancer in post-menopausal women. Formestane suppresses estrogen production from anabolic steroids or prohormones. It also acts as a prohormone to 4-hydroxytestosterone, an active steroid which displays weak androgenic activity in addition to acting as a mild aromatase inhibitor. It is listed as a prohibited substance by the World Anti-Doping Agency for use in athletes.


Formestane has poor oral bioavailability, and thus must be administered forthnightly (bi-weekly) by intramuscular injection. Some clinical data has suggested that the clinically recommended dose of 250mg was too low. With the discovery of newer, non-steroidal and steroidal, aromatase inhibitors which were orally active and less expensive than formestane, formestane lost popularity.


Currently, formestane (categorized as an anti-estrogenic agent) is prohibited from use in sports in accordance to the regulations of the World Anti-Doping Agency. It is not US FDA approved, and the intramuscular injection form of formestane (Lentaron) which was approved in Europe has been withdrawn.
Formestane (Lentaron) is a type I, steroidal aromatase inhibitor. It is used in the treatment of estrogen-receptor positive breast cancer in post-menopausal women. It is available as an intramuscular depot injection.


Formestane is often used to suppress estrogen production from anabolic steroids or prohormones. It also acts as a prohormone to 4-hydroxytestosteron, an active steroid which displays weak androgenic activity in addition to acting as a mild aromatase inhibitor.


Formestane has poor oral bioavailability and as such is no longer popular as many orally active aromatase inhibitors have been identified.


Applications


Formestane is a second generation, irreversible, steroidal aromatase inhibitor. It inhibits the aromatase enzyme responsible for converting androgens to estrogens, thereby preventing estrogen production. Breast cancer may be estrogen sensitive or insensitive. A majority of breast cancers are estrogen sensitive. Estrogen sensitive breast cancer cells depend on estrogen for viability. Thus removal of estrogen from the body can be an effective treatment for hormone sensitive breast cancers. Formestane has been targeted specifically for the treatment of postmenopausal women. Unlike premenopausal women who produce most estrogen in the ovaries, postmenopausal women produce most estrogen in peripheral tissues with the help of the aromatase enzyme. Formestane, an aromatase inhibitor, can thus help to decrease the local production of estrogen by blocking the aromatase enzyme in peripheral tissues (ie. Adispose tissue of the breast) to treat hormone sensitive breast cancer.

Our Adwantage


1.We have stock so we can delivery quickly at the very day when receive the payment.
2.Best price, first class service, high successful delivery rate. A discount would be given when you make a large order.
3.High quality guarenteed, once any problem is found, the package would be reshipped for you
4.Shipping by express (FedEx,UPS,DHL,EMS TNT HKEMS), by air.The most professional forwarder would be recommanded for you.
5. Warm after-sale service for you 24/7. Any of your question would be solved for the first as soon as possible.Adhering to the principle of customer first conviction.we will provide the best and the most sincere services as possible as we can.


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566-48-3 Raw Steroid Powders Formestane for Antitumor Anti-estrogenic Agent

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