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Peptide Steroid Hormones Tanning Melanotan Peptides CAS 121062-08-6 Melanotan II α-Melanocyte-stimulating Hormone

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Peptide Steroid Hormones Tanning Melanotan Peptides CAS 121062-08-6 Melanotan II α-Melanocyte-stimulating Hormone

China Peptide Steroid Hormones Tanning Melanotan Peptides CAS 121062-08-6 Melanotan II α-Melanocyte-stimulating Hormone supplier

Large Image :  Peptide Steroid Hormones Tanning Melanotan Peptides CAS 121062-08-6 Melanotan II α-Melanocyte-stimulating Hormone

Product Details:

Place of Origin: CHINA
Brand Name: Zhenxiang
Certification: HSE, ISO 9001, USP, BP
Model Number: 121062-08-6

Payment & Shipping Terms:

Minimum Order Quantity: Negotiable
Price: Negotiable
Packaging Details: Specials
Delivery Time: Within 8 hours after payment is confirmed
Payment Terms: T/T, Western Union, Money Gram, Bitcoin
Supply Ability: 500kg/month
Detailed Product Description
Molecular Formula: C50H69N15O9 Molecular Weight: 1024.180
CAS Registry Number: 121062-08-6 MeSH: Melanotan-II
Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2 Melanotan 2 Structural Name: Ac-cyclo[Nle4, Asp5, D-Phe7, Lys10]α-MSH4-10-NH2

Peptide Steroid Hormones Tanning Melanotan Peptides CAS 121062-08-6 Melanotan II α-Melanocyte-stimulating Hormone

Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2
Molecular formula: C50H69N15O9
Molar Mass: 1024.180
CAS number: 121062-08-6
PubChem: 92432
MeSH: melanotan-II


Melanotan 2 Structural Name: Ac-cyclo[Nle4, Asp5, D-Phe7, Lys10]α-MSH4-10-NH2

Melanotan 2 (also referred to as Melanotan II) is a synthetically produced variant of a peptide hormone naturally produced in the body that stimulates melanogenesis, a process responsible for pigmentation of the skin. This peptide hormone, called alpha-Melanocyte stimulating hormone or MSH, activates certain melanocortin receptors in the process of exerting its effects. Indeed, MSH also exerts potent influence over lipid metabolism, appetite, and sexual libido via these melanocortin receptors. As a result, Melanotan 2 has been shown in studies to exhibit appetite suppressant, lipolytic, and libido-enhancing effects in addition to promoting skin tanning. Melanotan 2 has been researched extensively for use in protecting against the harmful effects of ultraviolet radiation from sunlight due to its melanogenesis-stimulating properties.

 

Additionally, Melanotan 2 and a similar synthetically produced variant, known as PT-141, have been studied at length as a potential remedy for the treatment of sexual dysfunction; specifically, male erectile dysfunction.

 

Peptide Steroid Hormones Tanning Melanotan Peptides CAS 121062-08-6 Melanotan II α-Melanocyte-stimulating Hormone

 

The Development of Melanotan 2
The initial creation of the synthetic Melanotan 2 peptide can be credited to the University of Arizona. During the course of research aimed at developing a defense against skin cancer, focus was placed on developing a method of stimulating natural melanogenesis, or the natural production of melanin in the skin, without direct exposure to the potentially harmful ultraviolet radiation in sunlight. Initially, University of Arizona researchers attempted to directly administer the naturally occurring hormone alpha-MSH in order to elicit this desired result. Although this strategy exhibited promising results, it was determined that the naturally occurring MSH had a prohibitively short half-life to be of realistic use as a therapeutic remedy. However, the positive results gleaned from MSH administration encouraged further research into the development of Melanotan 1 and Melanotan 2, which exhibit similar effects whilst possessing an extended half-life for functional therapeutic utilization.

 

Melanotan 2 Studies and Further Information
Melanotan and Melanotan 2 are both analogs of the peptide hormone alpha-melanocyte stimulating hormone (α-MSH) that tend to induce skin tanning. Unlike Melanotan 1, Melanotan 2 has been shown to have aphrodisiac properties, the additional effect of increasing libido. Melanotan 2 is a cyclic heptapeptide analog of the alpha-melanocyte stimulating hormone (a-MSH).

 

The effects of Melanotan 2 on the diet and food intake of the laboratory mice have also been investigated. It has been demonstrated that the central melanocortin (MC) has been activated by melanotan 2 when fed and induced in the mice. The six-day treatment of Melanotan 2 has shown that the peptide actually reduced the body weight and the adipose tissue in the viscera of the mice and suppressed the caloric intake of the organism. This has implications in clinical applications of the possible treatment to reduce carbohydrate or calorie intake especially for the overweight and the obese. Furthermore, the same study has also demonstrated that there was a sustained increase in the available oxygen consumption in obese animals. Melanotan 2 also helped reduced the level of serum insulin and the cholesterol levels when compared with the control treatments. Furthermore, it has been suggested that melanotan 2 actually lowers the level of acetylcholine A caboxylase expression and even prevented the reduction of carnitine and palmitoltransferase I mRNA in muscle-type tissues by pair-feeding in the muscles of the obese rats. Moreover, the Melanotan 2 peptide actually increased the fat catabolism in the muscles and even improved the cholesterol metabolism (Li et al. 2004).

 

α-Melanocyte-Stimulating Hormone Analogues (Melanotan Peptides)
α-Melanocyte-stimulating hormone (α-MSH) is a naturally occurring endogenous melanotan peptide hormone of the melanocortin family, which is considered to be the most important of the melanocyte-stimulating hormones when it comes to stimulating melanogenesis, a process which in mammals is responsible for hair and skin pigmentation. α-MSH also plays a role in feeding behavior, energy homeostasis, and sexual activity (Bremelanotide and Melanotan 2). α-MSH is a nonselective agonist of melanocortin receptors MC1, MC3, MC4 and MC5. Melanotan 1 and Melanotan 2 activate the MC1 receptor, which is responsible for effects on skin pigmentation. Melanotan 2 and PT-141 both stimulate the MC3 and MC4 receptors which are responsible for the regulation of appetite, metabolism, and sexual behavior. However, PT-141 Bremelanotide does not stimulate the MC1 receptor.

 

A few synthetic analogues of α-MSH have been investigated for their apparent photoprotective effects against ultraviolet (UV) radiation from the sun, namely Melanotan (afamelanotide) and Melanotan II, referred to as Melanotan 2. Bremelanotide, another analogue of α-MSH similar to Melanotan 2, is currently under development for the treatment of sexual dysfunction. All of these melanotan peptides have significantly greater potencies than α-MSH, but with distinctive selectivity peptide profiles.

 

Our peptides list
Name Specification Purity≥
Purchase Peptides
ACE 031 foil bag 99%
Epithalon 20mg/vial 98%
Epithalon 50mg/vial 98%
Epitalon foil bag 99%
Follistatin-315 1mg/vial 98%
Follistatin 315 foil bag 99%
Follistatin-344 1mg/vial 98%
Follistatin 344 foil bag 99%
Adipotide 2mg/vial 98%
AOD9604 2mg/vial 95%
BPC 157 5mg/vial 98%
Thyrotropin TRH 2mg/vial 98%
MGF 2mg/vial 99%
PEG MGF 2mg/vial 99%
CJC-1295 DAC 2mg/vial 99%
CJC-1295 DAC 5mg/vial 99%
CJC-1295 2mg/vial 99%
GHRP-2 5mg/vial 99%
GHRP-2 10mg/vial 99%
GHRP-6 5mg/vial 99%
GHRP-6 10mg/vial 99%
Ipamorelin 2mg/vial 99%
Hexarelin 2mg/vial 99%
Sermorelin 2mg/vial 99%
Oxytocin 2mg/vial 99%
TB500(Thymosin Beta) 2mg/vial 99%
HGH Fragment 176-191 2mg/vial 99%
HGH Fragment 176-191 5mg/vial 99%
Triptorelin acetate 2mg/vial 99%
Tesamorelin 2mg/vial 99%
Gonadorelin 2mg/vial 99%
Gonadorelin 10mg/vial 99%
Melanotan Peptides
MT-1 10mg/vial 99%
MT-2 10mg/vial 99%
PT-141 10mg/vial 99%
Cosmetic Peptides
Argireline (Acetyl hexapeptide-3) foil bag 98%
GHK-Cu (Copper Peptide) foil bag 98%
Matrixyl (palmitoyl pentapeptide-3) foil bag 98%
SNAP-8 foil bag 98%
AHK (Tripeptide-3) foil bag 98%
AHK-Cu (Copper Peptide) foil bag 98%
Decapeptide-12 foil bag 98%
EYESERYL foil bag 99%
Eyeseryl (Acetyl tetrapeptide-5) foil bag 98%
Pal-AHK foil bag 98%
Pal-GHK (Palmitoyl Tripeptide-1) foil bag 98%
Pal-Lys-Val-Dab-OH foil bag 98%
Pal-Lys-Val-Dab-Thr-OH foil bag 98%
Palmitoyl Tripeptide-5 foil bag 99%
Peptide Blends
CJC1295,Ipamorelin,GHRP2 Blend foil bag 98%
ModGRF,Ipamorelin,GHRP2 Blend foil bag 98%
Sermorelin,GHRP2 Blend foil bag 98%
Sermorelin,GHRP6,GHRP2 Blend foil bag 98%
Other Peptides
DSIP 2mg/vial 99%
pentadecapeptide BPC 157 2mg/vial 99%
Selank 5mg/vial 99%
Follistatin-314 1mg/vial 98%
GDF-8 foil bag 99%
Deslorelin foil bag 99%
nonapeptide-1 foil bag 99%
Angiotensin foil bag 99%
Lanreotide foil bag 99%
Myostatin foil bag 99%
arelin Acetate foil bag 99%
Carbetocin Acetate foil bag 99%
Copper peptide(GHK-Cu) foil bag 99%
Terlipressin Acetate foil bag 99%
Exenatide acetate foil bag 99%
Fertirelina foil bag 99%
Octreotide acetate foil bag 99%
Goserelin acetate foil bag 99%
Thymosin α1 Acetate foil bag 99%
Serilesine foil bag 99%
Palmitoyl Tetrapeptide-7 foil bag 99%
Live Cell Growth Factor foil bag 99%
Palmitoyl Pentapeptide foil bag 99%
Myristoyl-Pentapeptide-17 foil bag 99%
Acetyl Glutamyl Heptapeptide-3 foil bag 99%
Nesiritide Acetate foil bag 99%
Eptifibatide foil bag 99%
Desmopressin acetate foil bag 99%
Teriparatide acetate foil bag 99%
Argipressine foil bag 99%
halodrol foil bag 99%

 

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